| abstract |
Disclosed is an anticancer agent containing a compound represented by formula (I), which is a compound having a superior inhibitory action on pim-1 kinase. (R 1 indicates a hydrogen atom, hydroxyl group, C 1-6 alkoxy group or the like; R 2 and R 3 indicate hydrogen atoms, halogen atoms, C 1-6 alkyl groups or the like; R 4 indicates a hydrogen atom, C 1-6 alkyl group, C 1-6 alkylsulphonyl group or the like; R 5 indicates a hydrogen atom or substituent; ---- indicates a single bond or double bond; R 6 and R 7 indicate hydrogen atoms, C 1-6 alkyl groups or the like; R 8 indicates a hydrogen atom, C 1-6 alkyl group or the like; A indicates -O-, -S-, or -CH 2 -; D indicates -C= or -N=; X indicates a methylene group, -O-, or -CO-; Q indicates -N= or -C(R 8 )=; and Y indicates a heterocycle group or amino group.) |