| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8713030703a70168a31c3f84c9967cc0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81d2b8093d2918dc88b96ac31bf47bb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de020b7dcbcaf745ca743fa95fa94853 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-365 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 |
| filingDate |
2011-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdb885a5642a4c58a6818f060276ef45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6de6b654e6f76ee39ab5e24b925653ef |
| publicationDate |
2011-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011131034-A1 |
| titleOfInvention |
4'-demethylepipodophyllotoxin derivative, preparation method and use thereof |
| abstract |
A 4'-demethylepipodophyllotoxin derivative of formula (III) having anti-tumor activity is provided. After the activation of hydroxyl in position C4 of 4'-demethylepipodophyllotoxin, tetramethylpyrazine is introduced by transamination to obtain the 4'-demethylepipodophyllotoxin derivative which is preferably used to inhibit gastric cancer cell line BGC-823. |
| priorityDate |
2010-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |