http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011130737-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e641224069b7d2206668f6581d731a60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5810f525dede938db3425487970e17d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59c6a921f33fe0adc58c2b6177184515 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2220-86 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-262 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-405 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-34 |
| filingDate | 2011-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab3fbf361c6bc1b0e907b120bf04dfc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_489dbb31449de7e51fc6b4f806ec9d93 |
| publicationDate | 2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2011130737-A2 |
| titleOfInvention | Materials and methods for capillary microextraction in combination with high-performance liquid chromatography |
| abstract | Germania-based sol-gel organic-inorganic hybrid coatings were prepared for on-line coupling of capillary microextraction with high-performance liquid chromatography. For this, a germania-based sol-gel precursor, tetra-«-butoxygermane and a hydroxy-terminated triblock copolymer, poly( ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) were used. These sol-gel germania triblock polymer coatings were chemically anchored to the inner walls of a fused silica capillary (0.25 mm I.D.). Scanning electron microscopy images of the sol-gel germania triblock polymer coating were obtained to estimate the coating thickness. For the first time, the analyte distribution constants between a sol-gel germania organic-inorganic hybrid coating and the samples (K cs ) were determined. For a variety of analytes from different chemical classes, including polycyclic aromatic hydrocarbons (PAHs), ketones, alcohols, phenols, and amines, the K cs values ranged from 1.8 x 10 1 to 2.0 x 10 4 . Also, for the first time, the high-temperature solvent stability of a sol-gel germania-based coating was evaluated. The sol-gel germania triblock polymer coatings were capable of surviving exposure to high temperature solvent conditions (200°C) with little change in extraction capabilities. This demonstrates that sol-gel germania triblock polymer materials might be suitable for further applications in high-temperature HPLC. The reproducibility of the method for preparation of the sol-gel germania triblock polymer coatings was also evaluated, and the capillary-to-capillary RSD values ranged from 5.3% to 6.5%. The use of higher flow rates in extraction was found to significantly reduce the time required (from 30-40 minutes to 10-15 minutes) to reach equilibrium between the sol-gel germania triblock polymer coating and the analytes in the sample solution. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106111096-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106111096-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105944700-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103163259-A |
| priorityDate | 2010-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.