Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39fa717fd31ee23fde89283e534c3781 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80c3f56138cb460532ffaeaff92b0d8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f931c6084051cbf0ef8dd1a621fff5dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc42cfc57f1e2d5c0c3f3dbfa0e90675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6adf430865cacd72ef3f39dc16720676 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-3156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-315 |
filingDate |
2011-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b04e04f5adf6bd962accc297613a0e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_814a392cf92de909473bbf6269177ca8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_371a75085245bc81903e0802aa37419a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e59b1da46098529f200c6849bbee504a |
publicationDate |
2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011128892-A2 |
titleOfInvention |
Modified forms of pneumococcal surface immunogenic protein b (psipb) |
abstract |
The present invention relates to modified forms of the protein Pneumococcal surface immunogenic protein B (PsipB) derived from Streptococcus pneumonia (S. pneumoniae). The modified PsipB polypeptides and fragments have enhanced immunogenicity, stability at physiological pH formulation and formulation properties as compared to wild type PsipB. The invention further provides immunogenic compositions and vaccines comprising the modified PsipB polypeptides and fragments, and use thereof in methods for eliciting protective immunity to S. pneumoniae. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9393294-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188717-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11207375-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10105412-B2 |
priorityDate |
2010-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |