| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_785ac2b35073f5a6d251678e6fb31b6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c285b3019257a0e5fd147734aaa1b54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_604e07c32377cab416660b10fd8f494c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9f8f7395aa059c69d00a60516c4c9b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e6e6e98bd11d780292dfe30923b7bd7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-346
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3231 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2011-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba12a35937fdbd17cbf3c02690a1525d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de3fe8a500b45418aeaa868c6d197779
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68f2e3515b2cad372f60d7b4233360c9 |
| publicationDate |
2011-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011123394-A1 |
| titleOfInvention |
Modulation of matrix metalloproteinase 13 (mmp-13) expression |
| abstract |
Disclosed herein are antisense compounds and methods for decreasing MMP-13 mRNA and protein expression. Also disclosed herein are methods for reducing osteoclastogenesis, osteolysis, osteoclasts, and TGF-beta signaling; methods for inhibiting tumor growth; methods for decreasing bone destruction and gelatinolytic activity; and method for treating or preventing metastasis of hyperproliferative diseases in an individual in need thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10287584-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016077540-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016019225-A1 |
| priorityDate |
2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |