| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2c27c903c77e0cf3aa8f750e34bdf24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdd5f5ab0ec9138f78c572f3fdc60dd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69e1a070ea4baa5df9b91d1b482f5c17 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e50e805d279e01a9cf715f4246b2f21e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67c2df111e9ac96f3b1f3b6c21813f65 |
| publicationDate |
2011-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011123103-A1 |
| titleOfInvention |
System and method for anti-cancer drug candidate evaluation |
| abstract |
The disclosure provides a method of evaluating the ability of an anti-cancer drug candidate to induce apoptosis in a known cancer cell line by placing a single-cell suspension of a known cancer cell line in a well of a plate, adding at least one drug candidate to the well in an amount sufficient to achieve a target drug candidate concentration, measuring the optical density at selected time intervals for a selected duration of time, determining a kinetic units value from the optical density and time measurements, and correlating the kinetic units value with an ability of the anti-cancer drug candidate to induce apoptosis in the cancer cell line if the kinetic units value is positive. A similar method may be used to evaluate the ability of an anti-cancer drug candidate to induce apoptosis in a cancer type. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015517662-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104704368-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015193702-A1 |
| priorityDate |
2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |