| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96f6c63f61dc125e1509db7465e646a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ec257e5c20bbc7ce64020f4828b8ccf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bca1bc9b5300ec4d40a59fe0d5223e8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 |
| filingDate |
2011-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acd7fb2b43f9378de9004ab268a95349
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82610d9f6b68c8d46738c0321392d884 |
| publicationDate |
2011-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011113005-A2 |
| titleOfInvention |
Compositions and methods for combinations of oligoamines with 2-difluoromethylornithine (dfmo) |
| abstract |
The present invention is based on the seminal discovery of a synergistic effect for combinations of oligoamines with 2-difluorornethylornithine (DFMO) for treatment of cancer. The invention provides combinations of at least one inhibitor of a histone demethylase enzyme and at least one inhibitor of ornithine decarboxylase (ODC). The invention also provides methods for treatment of cancer using such combinations and methods for altering methylation in a cell using such combinations. The invention provides that certain silenced genes can be re-expressed using combinations disclosed herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023017262-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11013698-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233178-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10265279-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10214477-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10202330-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524717-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10221125-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10780081-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10329256-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9944601-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9908859-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9670136-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018004467-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9790196-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9181198-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9186337-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11234945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9061966-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9708309-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9676701-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012107499-A1 |
| priorityDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |