| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_575ae50dac6d38d37410965b5f20bf0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64e8021557b103ab6686ff694052be69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85257aeea4ad39d472d64a3abca21e17 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2011-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0d730fbac26cabb84bea3a0680d654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88a56545756d43722432f52505ad9bc7 |
| publicationDate |
2011-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011112397-A2 |
| titleOfInvention |
Mrna as biomarkers for liver injury or other liver perturbations |
| abstract |
The present invention provides a method for assessing the likelihood or for detecting the presence of liver perturbation in an individual. The method is particularly useful for detecting drug-induced liver injury (DILI) or other forms of hepatotoxicity or hepatic perturbation. The method comprises measuring the level of at least one RNA biomarker comprising mRNA and comparing the measured level to an appropriate reference value for the sample type and RNA biomarker type, and wherein a significant difference between the measured level and the reference value is indicative of liver perturbation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110964804-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106582-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014078896-A1 |
| priorityDate |
2010-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |