| abstract |
A formulation for delivery of a therapeutic agent to the small intestine which features a combination of a single delayed release mini-tablet for delivery to the gastrointestinal tract, surrounded by a fast disintegrating tablet layer which dissolves in the oral cavity. The oral disintegrating tablet which undergoes rapid disintegration in the oral cavity supports ease of swallowing and hence ease of administration of the mini-tablet, which is responsible for delayed release of a therapeutic agent in the small intestine. The mini-tablet preferably has a relatively small diameter, smaller than that of a regular tablet. |