| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_588f4799eeda38576f3d4784cef85ded
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_beea9cce75d52016f4bb0489a9f9ac00 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
| filingDate |
2011-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e06b440cb155de6eef49a7dfe5031cd |
| publicationDate |
2011-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011109380-A1 |
| titleOfInvention |
Nucleic acids for targeting multiple regions of the hcv genome |
| abstract |
Compositions and methods effective for modulating Hepatitis C viral infection are provided. Compositions and methods effective for modulating Hepatitis C viral infection are provided. Specifically, multiple artificial miRNAs targeting different regions of the HCV genome were inserted into a single promoter, polycistronic expression vector. The exogenous anti -HCV miRNAs induced gene silencing. When expressed from an adenovirus associated virus (AAV) delivery system, the vector inhibit the replication of HCV without inducing toxicity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022233982-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11767531-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7183167-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020518552-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10888628-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779656-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3788141-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3576752-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11352629-B2 |
| priorityDate |
2010-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |