| abstract |
This invention relates to a list of apoptosis-inducers consisting of 6-bicycloaryl substituted 5,6-dihydro-2 H -pyran-2-one derivatives. According to the present invention, the apoptosis-inducers trigger cell death by expression of a list of apoptotic genes, so they can be useful for the treatment of cancers, or other autoimmune diseases suffering from the lack of apoptosis such as viral infections, diabetes type I, or encephalomyelitis. |