Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be76fbd82a0aaab4f4a9537106e3c21e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd5080a2c880b5e0947ad728e6b2c1a1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6939 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
filingDate |
2011-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_974b1e347dd13cb107eae50e83b0a0f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b415d074cece9984b756933c2d0626f5 |
publicationDate |
2011-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011088456-A2 |
titleOfInvention |
Methods and compositions for nanoparticle-mediated cancer cell-targeted delivery |
abstract |
The present invention provides methods and compositions to selectively and directly deliver nanoparticles carrying an active agent to tumor cells. The active agent is internalized by the tumor cells, producing an anti-tumor effect for therapeutic applications and/or depositing a detectable marker for diagnostic applications. The present invention further provides a p53 chimera that circumvents the dominant negative activity of mutant p53 as a therapeutic in the treatment of cancer and reduction of tumor size. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9486540-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2019370892-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013134777-A1 |
priorityDate |
2010-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |