Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b613a6eb569a2f844fa3a1783298313c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aba232d425c6d26a4f7bf096b08b203a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48eb1edee350c15fc30eeffcf1c5b6f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2011-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a76e4ee7660de64b8d95d1665fb0981 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3574af060eccf8d24ad9dd4a952edbcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e0ad1c324b9b3b97d2902efe5703b98 |
publicationDate |
2011-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011088163-A1 |
titleOfInvention |
Methods for modulating skeletal remodeling and patterning by modulating shn2 activity, shn3 activity, or shn2 and shn3 activity in combination |
abstract |
This invention is based, at least in part, on the discovery that Shn2 and Shn3 play an important role in skeletal remodeling and skeletal patterning. Accordingly, the present inventon provides methods for identifying medulators of Shn2 activity and methods for modulating bone formation and mineralization and Shn2-associated disorders using agents that modulate Shn2 expression and/or activity, in addition to methods for modulating Shn2 and Shn3. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4169576-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9745589-B2 |
priorityDate |
2010-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |