http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011085015-A3

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filingDate 2011-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e2db049e317b4cbbf67e7eca6bbc424
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publicationDate 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2011085015-A3
titleOfInvention Skin lightening compositions
abstract Compositions and methods for lightening and/or depigmenting skin are provided, the compositions comprising compounds having the structure: Formula (I), wherein: R 1 and R 2 are same or different and are each selected from the group consisting of hydrogen, alkyl, carbomethoxy, carboethoxy, alkoxy, and alkanoyl, any of which may be halogen-substituted, and halogen; R 6 is selected from the group consisting of hydrogen, methyl, and ethyl; and R 3 , R 4 and R 5 are the same or different and are each selected from the group consisting of hydrogen, methyl, methoxy, ethoxy, methoxyethoxy, ethoxyethoxy, propoxy, propoxymethoxy, and the like, any of which may be halogen-substituted; or having the structure: Formula (II), wherein: R 2 is hydrogen, lower alkyl or hydroxy lower alkyl; R 3 is lower alkyl, -CH 2 CN, hydroxy lower alkyl, -NO, -CH 2 N=C or (wherein R 6 and R 7 are independently selected from the group consisting of hydrogen and lower alkyl) or hydrogen provided R 2 is not hydrogen; R 4 is Z-T-W wherein Z represents -O-, -NH- or a single bond; T represents a straight- or branched-chain lower-alkylene group; when Z is a single bond, T also represents an ethenylene or a propenylene group wherein the unsaturated carbon is at the single bond; when Z is -O-, T also represents an allylene group wherein the saturated carbon is at the oxygen; and W represents hydrogen, when T is allylene and Z is -O-, and Ar, wherein Ar is selected from thienyl, pyridinyl, furanyl, phenyl and substituted phenyl wherein there are one or more substituents on the phenyl independently selected from halogen or lower alkyl; and R 5 is hydrogen, halogen or lower alkyl; or pharmaceutically-, cosmetically- and dermatologically-acceptable salts, solvates, and bioprecursors, and stereoisomers and enantiomers of these compounds, free from or mixed with other enantiomers or stereoisomers; and such compounds in compositions with a pharmaceutically-, cosmetically- or dermatologically-acceptable carrier thereof comprising a safe and effective amount of the skin lightening or depigmenting compound.
priorityDate 2010-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 46.