http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011082700-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d90a0196d350e4b3c70a2d96d4cea65b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fece74aa8c0cb73d997c194165159cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2678584c4f8e2d70ca75a7e13f16cee3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-18 |
| filingDate | 2011-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2457aeffed4210a2374b7c861bd80fbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a483c6dc37a6faf9bad504bc29d1bb2 |
| publicationDate | 2011-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2011082700-A1 |
| titleOfInvention | A method for the preparation of 6,7-dimethoxy-1-[2-(4-trifluoromethylphenyl)ethyl]-3,4- dihydroisoquinoline |
| abstract | The invention relates to a method of preparing 6,7-dimethoxy-l-[2-(4-trifluoromethylphenyl) ethyl]-3,4-dihydroisoquinoline I by cyclization of substance III, wherein the R substituent is a C1-C4 alkyl group, under conditions of acidic catalysis, the acidic catalyst being a strong inorganic acid, polyphosphoric acid or phosphorus oxychloride. The compound of formula (I) represents the key intermediate of synthesis of almorexant. (Formulae (I), (III)) |
| priorityDate | 2010-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.