| abstract |
Disclosed are: a prophylactic or therapeutic agent for hyperlipemia, which contains a carnosinase inhibitor and L-carnosines; and an anti-fatigue agent which contains a carnosinase inhibitor and L-carnosines. The free fatty acid concentration in the plasma of a mammal can be decreased by the combined use of a carnosinase inhibitor and L-carnosines. In addition, the lactic acid concentration in the plasma can be decreased by the combined use of a carnosinase inhibitor and L-carnosines, thereby reducing fatigue, enhancing recovery from fatigue and improving endurance. Preferable examples of the carnosinase inhibitor may include ß-alanine, N-alkanoyl-ß-alanine derivatives, N-alkanoyl-L-carnosine derivatives and the like, and preferable examples of the L-carnosines may include L-carnosine, N-acetyl-L-carnosine, L-anserine, N-acetyl-L-anserine, L-balenine, L-homocarnosine, N-acetyl-L-homocarnosine, carcinine and the like. |