http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011073746-A2

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filingDate 2010-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edde6dd2bc21e13ff8ebabc9c2a3c336
publicationDate 2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2011073746-A2
titleOfInvention Calibration of electrochemical sensor
abstract This invention is concerned with electrochemical methods of analysing a fluid for an analyte. It utilises a sensor comprising electrodes and a mediator compound capable of undergoing a cycle of oxidation and reduction in response to varying potential applied to the electrodes, where the compound is also able to undergo a portion of the cycle through chemical reaction with the analyte. As is already known, the sensor is used in a method in which the sensor and the fluid are brought into contact sufficiently for the analyte to react chemically with the mediator, and in a voltammetry procedure, potential is applied to the electrodes while observing current flow with sufficient time for reaction between the mediator compound and the analyte, for thereby observing the concentration of the analyte. The novel characteristic of this invention is a step of calibrating the sensor by applying a rapidly changing potential to the electrodes and observing current flow, the change of this potential and observation of current being sufficiently fast to allow and observe electrochemical oxidation and reduction of the mediator taking place independently of the concentration of analyte, thereby observing the concentration of the mediator compound. The rapid change of potential maybe provided by pulse voltammetry or square wave voltammetry.
priorityDate 2009-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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