| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f985d63987a078ba9db724f6d7e4c74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c45f3f15395ecd80506aa6c37fe3cb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95ce153a79848445e6dd9e26f15387f5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2010-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b5732f66db8bff70622f66b5dd53cbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5636706b42482efa4046215701cdcc8 |
| publicationDate |
2011-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011071078-A1 |
| titleOfInvention |
Aromatic compound, modification carrier that uses same and is used for synthesizing an oligonucleotide derivative, oligonucleotide derivative, and oligonucleotide construct |
| abstract |
Provided is an oligonucleotide derivative, the 3′ end of which is chemically modified with two skeletons selected from among benzene skeletons and pyridine skeletons. Said oligonucleotide derivative can be easily synthesized in a small number of steps. Also provided is an aromatic compound that serves as a precursor for preparing a modification carrier for synthesizing the oligonucleotide derivative. The oligonucleotide derivative and a provided oligonucleotide construct have good cell membrane permeability and excellent nuclease resistance. The aforementioned modification carrier is characterized in that the carrier is chemically modified, via a linker, with the unit represented by structural formula (a) (in which R 1 through R 6 each independently represent hydrogen or a non-hydrogen substituent, Z 1 and Z 2 each independently represent CH or nitrogen, and X represents oxygen or sulfur). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018524387-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017047594-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014195438-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017047594-A1 |
| priorityDate |
2009-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |