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publicationDate 2011-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2011065867-A2
titleOfInvention Liposomes containing oligopeptide fragments of myelin basic protein, a pharmaceutical composition and a method for treatment of multiple sclerosis
abstract A pharmaceutical composition for treatment of Multiple Sclerosis is disclosed, comprising monolamellar liposomes having the size of 100 nm to 200 nm, wherein the liposomes comprise a mixture containing 1 part by weight of tetramannosyl-3-L-lysine-dioleoyl glycerol and 99 parts by weight of 2,3-dipalmitoyl-sn-glycero-1-phosphatydyl choline, and includes the following oligopeptides: GGDRGAPKRGSGKDSHH; GFGYGGRASDYKSAHK; QGTLSKIFKLGGRDSRSGSPMARR, which are myelin basic protein fragments. A method for treatment of Multiple Sclerosis, comprising administering said pharmaceutical composition to a patient in need thereof is also disclosed.
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