| abstract |
Disclosed is a substituted oxopiperazine compound which is useful as an agent for the treatment of hypertension and the like.nSpecifically disclosed is a compound represented by general formula (I) or the like.n(In the formula, R 1 represents an optionally substituted adamantyl group; R 2 represents H or an alkyl group; R 3 represents H or a substituted carbonyl group; R 4 represents H or an alkyl group; R 5 represents H or an alkyl group; and R 6 , R 7 and R 8 each represents H, an optionally substituted alkyl group, an optionally substituted hydroxy group, a halogeno group or the like.) |