Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec064e15ad58a288ff72eddef3ec3cab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d426457a9362189a3062f4ced2ea02a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c56712bcd91b75ca6a68e259d0fc7b80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5281b773800f0fca8ffff90b13980c66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b603ecd95b3b1497ae9f30752a676c0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9f84200d949acd519611e696dd580b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e47d3aabadfc8b954469b005b6f91a59 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2010-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92c94acf37ca485e1bc99a503be5d0a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9972b731b209ab9d1271f292647a2dbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1cec1b5583c004371e7edc20945eccd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a79ac8840aeba8ef731fd92be55454bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94d82a733b3675df3dfc1b187558c101 |
publicationDate |
2011-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011058143-A1 |
titleOfInvention |
Signature for the diagnosis of breast cancer aggressiveness and genetic instability |
abstract |
The present invention relates to a method for diagnosing aggressiveness and/or genetic instability of a breast cancer in a patient from a breast cancer sample of said patient, comprising: a) measuring in vitro the expression level of the POLQ gene and the expression level of a control gene in said patient breast cancer sample; b) calculating for said POLQ gene an expression level ratio of the expression level of POLQ to the expression of the said control gene in said patient breast cancer sample; c) comparing the said POLQ expression level ratio to a corresponding threshold value, and d) diagnosing breast cancer aggressiveness and genetic instability if the said POLQ expression level ratio is superior to a corresponding threshold values. Dedicated microarrays and kits are also described, as well as a method of selecting a suitable treatment. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102994627-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102994627-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013102680-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9790556-B2 |
priorityDate |
2009-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |