http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011057354-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8ab5f1ee8c441b66ad2873b5e0f669f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d26689c40b6094971b3c16fe3bf1cfce http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fc0668fd5cbfe23cea7d9bdd5de932a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2010-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97612070954963fb35ddc27b67241d3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4405f92a78a01c0994246ec46853a606 |
publicationDate | 2011-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2011057354-A1 |
titleOfInvention | Epigenetic analysis |
abstract | Provided herein are methods for the analysis of methylation in nucleic acid molecules, comprising bisulfite conversion and subsequent copying or amplification in the presence of a ligand-labelled dCTP or a ligand-labelled dGTP incorporated at the site of a cytosine or complementary guanine, respectively, at positions corresponding to methylated cytosines in the bisulfite-treated nucleic acid or after the copying or amplification, subjecting the resulting nucleic acid molecules to restriction endonuclease digestion with an enzyme which comprises a cytosine nucleotide in its target recognition sequence to generate nucleic acid fragments with termini proximal or adjacent to one or more cytosines and attaching a ligand or oligonucleotide adaptor and subsequently amplifying the nucleic acid molecules. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180029200-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101903932-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021258032-A1 |
priorityDate | 2009-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 238.