| abstract |
The present invention relates to a method for detecting an analyte, such as glucose, using Surface Enhanced Raman Spectroscopy (SERS), including contacting the analyte with one or more compounds selected from the group consisting of aryl boronic acid derivatives, heteroaryl boronic acid derivatives, aryl boronate derivatives and heteroaryl boronate derivatives attached to a metal surface that enhances Raman scattering, in particular a nanoparticle surface; and detecting a surface enhanced Raman signal from said compound. The invention further relates to new receptor compounds useful in such a method as well as biosensors including these compounds, optical fibers including such biosensors and methods of using these receptor compounds, biosensors and optical fibers for analyte detection. |