abstract |
The present invention relates to a gastric-retentive sustained release formulation containing pregabalin or a pharmaceutically acceptable salts thereof, polyethyleneoxide, and polyvinylalcohol-polyethyleneglycol graft copolymer, in which a swelling property and floatability of matrix is improved by using a polyethyleneoxide and polyvinylalcohol-polyethyleneglycol graft copolymer, thereby controlling the release of the drug. |