Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97f9429fd114320bcef9d1842469f95e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7825255bdffe8bc22af3247ec0622302 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e9aee13868bfedebe2df1f13cda5490 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdc4078753c8c6b736a792917fa4ad21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c58cece7ce0dfd90845a0be4757c1d3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-12 |
filingDate |
2010-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ec262b498ffcda336f287660c550a1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_093a7084c1e56115e7013ea97146676e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ae2cae249d029fb2ae67ac069695b5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64feb3ef4f30bdd1ad813d2119d772a5 |
publicationDate |
2011-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011046007-A1 |
titleOfInvention |
Process for preparation of diethylenetriaminepentaacetic acid derivatives, and diethylenetriaminepentaacetic acid derivatives |
abstract |
Provided is a process for preparing easily and efficiently an intermediate compound for use in the synthesis of a gadolinium complex which has a substituent capable of improving retention in blood or organ specificity. Also provided is an intermediate for the synthesis which has been prepared by the process. A process for the preparation of diethylenetriaminepentaacetic acid derivatives (I) [wherein R 1 to R 5 are each independently C 1-6 alkyl], characterized by including: a step of reacting a diethylenetriaminepentaacetic acid pentaester with a halogenated allyl compound; a step of removing the residual part of the halogenated allyl compound; and a step of reacting the reaction product, which has been formed by the reaction of the diethylenetriaminepentaacetic acid pentaester with the halogenated allyl compound, with a base in a solvent. |
priorityDate |
2009-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |