| abstract |
Substituted phenylcarbamoyl alkylamino arenes; substituted phenylthiocarbamyl alkylamino arenes; substituted phenylcarbamoyl alkylamino heteroarenes; substituted phenylthiocarbamyl alkylamino heteroarenes; N-substituted aryl, N'-subsituted aryl urea compounds; N-substituted aryl, N'-subsituted heteroaryl urea compounds; N-substituted aryl, N'-subsituted aryl thiourea compounds and N-substituted aryl, N'-subsituted heteroaryl thiourea compounds are provided and may find use as androgen receptor modulators. The compounds may find particular use in treating prostate cancer, including CRPC and/or hormone-sensitive prostate cancer. |