Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01598561d1bcf6cb9d0f4b0cfd7f3ade http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cf7f3f36d20185ce15a2d1f04d5fdc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b72074f5eae6e964d7d4fdb80860dc4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4eb08f3902c26ad9e1d2f0eaf310862 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7de2791dd613ba76a789c76d139d974f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab076dbaa11ba7c868d14dcc15765a6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff9693ee0a2ccb02014ab0fe5913dc49 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216 |
filingDate |
2010-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4399a37ccceacd31371de4372ee3a503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6406cae11906a4eebe7fca02bde864d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f50566a20660c67358cb276228bb17f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_744931de9c68dd73532db043c2fc21bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81892b96f917745446bcbd4530182b93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0eedfbf223e7b878f7f07074703a23e1 |
publicationDate |
2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011042420-A1 |
titleOfInvention |
Delivery system for sustained release of a calcium -channel blocking agent |
abstract |
A delivery system for sustained release of a calcium-channel blocking agent is adapted for introduction in the cerebrospinal fluid of a subject. The delivery system comprises a solid dispersion product of a calcium-channel blocking agent in a mixture of a (i) first poly(lactide-co-glycolide) having a molecular weight distribution centered around a first number average molecular weight Mn1 and a (ii) second poly(lactide-co- glycolide) having a molecular weight distribution centered around a second number average molecular weight Mn2, wherein Mn1 is in the range of from 2000 to 3000 g/mol and the ratio of Mn1/Mn2 is from 1.8 to 3.5. The delivery system is deposited in the vicinity of or adjacent to a blood vessel showing vasospasm or suspected of developing vasospasm. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014271772-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10708809-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9700549-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10543201-B2 |
priorityDate |
2009-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |