Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d41755fcc0f638a41193caaf443af2bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f528506b0bafd41a133f300bc6ec221a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-706 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2010-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f85854b14bfc03244c43d6019e1c815f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e13c2a6b328de509a277cd8f69e15a63 |
publicationDate |
2011-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011039612-A1 |
titleOfInvention |
Detection and use of antiviral resistance mutations |
abstract |
The present invention relates generally to viral variants exhibiting reduced sensitivity to anti-viral agents. More particularly, the present invention is directed to Hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs or other anti-viral agents and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies or other anti -viral agents. Vaccines and diagnostic assays are also contemplated herein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013078786-A1 |
priorityDate |
2009-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |