| abstract |
The invention relates to a pair of primers capable of amplifying the pol gene of the human immuno deficiency virus (HIV), allowing the detection of HIV in biological samples that exhibit a low viral load. The HIV RNA thus detected may be genotyped in order subsequently to establish a mutation profile showing resistance to antiretroviral therapy (ART) in HIV, in patients presenting a low viral load, to be used for the early detection of mutations which, in HIV, are responsible for the failure of ART, even in cases where plasma viremia levels are low, which makes it possible to modify the therapy early on to prevent the appearance of new mutations and to safeguard the efficacy of drugs in the current therapy regimen and of others that might be administered in the future. |