Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7946ec4f3ab0ccdf6d369bf5079567ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad25619578d5678963fcde652473b880 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bddb8d034cec46597e523fdfee85310f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b2dd7932639f26b31663efdb6ebe4df http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b910e6f782e46ce9a5b940e5484b1451 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate |
2010-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_921ba000693ac785e883024756ca72d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5ade77c89c4bf696411f911e473fb18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f5fd6ba9a862f74be4e0b5677b3e7fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45350cd9ea1f0432eb695913cfbe81a0 |
publicationDate |
2011-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011033105-A1 |
titleOfInvention |
Dosage regimen for administering an epcamxcd3 bispecific antibody |
abstract |
The present invention relates to a method (dosage regimen) for administering an EpCAMxCD3 bispecific antibody to a human patient, comprising (a) administering continually a first dose of said antibody for a first period of time; and consecutively (b) administering continually a second dose of said antibody for a second period of time, wherein said second dose exceeds said first dose. The methods of the invention (and likewise the dosage regimen of the invention) are also suitable for treating EpCAM positive epithelial cancer cells in a human patient, or for ameliorating and/or preventing a medical condition mediated by the continued administration of an EpCAMxCD3 bispecific antibody to a human patient. The present invention also relates to the use of an EpCAMxCD3 bispecific antibody for the preparation of a pharmaceutical composition to be used in a method as defined in any one of the preceding claims. A pharmaceutical package or kit comprising the first dose and the second dose as defined in the methods/dosage regimen of the present invention is disclosed as well. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11713358-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013083809-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019051102-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110678228-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IL-273119-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3409322-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018219901-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11787851-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11753461-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11744893-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4129327-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11459404-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11744892-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11406710-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2956483-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3341009-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11685780-B2 |
priorityDate |
2009-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |