| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_282d8844066f5f683bc2463742373508
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c92d4a62df5f94768694363768d0a0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_638336aa54551464013be94ef40d5fb0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_584666f2b0a05e89725ca5794c85e904
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa03b54c1e2494223917c9bd9e5edde8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2010-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3da722ccc95482886bd7cbfd98e9a268
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bfe0b48b6896bc08679802653b03b18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597812f944de7f13b4aff023b3e9aadf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b65c93a69b9889a9af6406cf10c106da |
| publicationDate |
2011-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011033005-A3 |
| titleOfInvention |
Cells for transient expression and uses thereof |
| abstract |
This invention relates to the transient expression of heterologous polypeptides in mammalian cell lines. Specifically it relates to an expression-enhanced cell line derived from a parent cell line, the expression-enhanced cell line comprising nucleic acid encoding Epstein-Barr Virus Nuclear Antigen 1 or a functional derivative, analogue, or variant thereof; and further comprising: (a) a nucleic acid encoding an exogenous glutamine synthetase; (b) a nucleic acid encoding an endogenous glutamine synthetase, wherein the endogenous glutamine is arranged to have enhanced enzymatic activity and/or enhanced expression relative to the parent cell line under comparable conditions; or (c) both (a) and (b). |
| priorityDate |
2009-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |