Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_72b9e8769d05872ab0d38da6c7a6ddeb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-606 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
2010-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b7562e48f26fb3586743b759b85e965 |
publicationDate |
2011-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011032166-A2 |
titleOfInvention |
Reprogramming blood cells to pluripotent and multipotent stem cells |
abstract |
The present invention is based on the seminal discovery that cord blood (CB) and adult bone marrow (BM) CD34+ cells can be reprogrammed to early stem cells. The invention provides the reprogramming of CB and adult bone marrow (BM) CD34+ cells from subjects without any pre-treatment. Provided are methods for reprogramming blood cells of a subject. Also provided are methods of disease modeling and methods of generating subject- specific differentiated cells. In addition, the invention provides methods of identifying an agent that alters a function of subject-specific differentiated cells as well as isolated pluripotent or multipotent stem cells reprogrammed from blood cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10221396-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012174467-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261429-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012131387-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9404124-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261433-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150014512-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016097036-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102066761-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3206498-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9347044-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104471060-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2013176233-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2853592-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013264708-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8741648-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017130205-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9963681-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10260048-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012174467-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104471060-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8691574-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9447382-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011119942-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10519425-B2 |
priorityDate |
2009-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |