| abstract |
Disclosed are disubstituted or trisubstituted quinoline compounds represented by the following general formula (I) or their pharmaceutically acceptable salts or solvates, which are used as c-Met inhibitors, their preparation methods, pharmaceutical compositions containing the same and uses of these compounds for preparing medicaments for preventing or treating diseases relating to cell abnormal proliferation and morphological variation associated with hepatocyte growth factor (HGFR) in organism, diseases relating to hyperkinesia and diseases relating to angiogenesis or metastasis, especially medicaments for treating or preventing tumor growth and metastasis. |