Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32c6d60259506a2cb9909dbaa777b9e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebc9a00e2fc4836aef3f39b224ca4d2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db8acd71f5994544bda6df3f27a3f51e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4ee134516e680ba5085b139072f6327 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2010-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_665d6d1b70b20ffa51f188eb527ecaa1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5f14fc16a934938655e06903fbdfc27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b4546a57be18c1e5a4b0b0ac25d4677 |
publicationDate |
2011-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011022820-A1 |
titleOfInvention |
Binding-induced hairpin detection system |
abstract |
This application relates to a binding-induced hairpin detection system comprising: a. a first probe comprising a targeting molecule and an oligonucleotide that has a free end and an end attached to the targeting molecule; and b. a second probe comprising a targeting molecule and an oligonucleotide that has an end attached to the targeting molecule and a free end comprising a nucleotide sequence that is complementary to a nucleotide sequence at or near the free end of the oligonucleotide of the first probe; wherein upon binding of the targeting molecule to a target molecule, the free end of the oligonucleotide of the second probe hybridizes at or near the free end of the oligonucleotide of the first probe forming a hairpin stem, the non-hybridized portions of the first and second probes together with the target molecule bound thereto forming a hairpin loop, thereby providing a binding-induced hairpin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208676-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106715724-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4108781-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020193977-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3464636-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015118029-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11034995-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020242380-A1 |
priorityDate |
2009-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |