| abstract |
The invention relates to FGF receptor-activating N-acyl octasaccharides having Formula (I), wherein: R 1 is an O-alkyl group optionally replaced by one or more aryl or cycloalkyl groups, R 2 is an OSO 3 - or hydroxyl group, R 3 is an alkyl, cycloalkyl, or alky-cycloalkyl group, R 4 is a disaccharide having Formula (II), R 6 is a disaccharide having Formula (III), and R 8 is a disaccharide having Formula (IV), where R 5 , R 7 , and R 9 have OSO 3 or hydroxyl groups. The invention further relates to the preparation of said octasaccharides and to the therapeutic use thereof. |