| abstract |
The present invention relates to the use of a compound of the following formula (I), as an enzyme substrate for the detection of a peptidase activity or as a pH indicator: according to which: • Y 1 is a peptide, H or an alkyl • W 1 , W 2 , W 3 and W 4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination thereof • n = 0, 1 or 2 • U is N or N + R and V is CZ 6 N or N + R or else V is N or N + R and U is CZ 6 , • R is H, alkyl, aralkyl, aryl, alkanoic or alkylsulphonic • Z 1 , Z 2 , Z 3 , Z 4 and Z 5 are independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulphonyl, including the carboxyl or sulphonyl esters or amides and salts thereof. |