| abstract |
According to the invention there is provided a compound of formula (I) wherein: A represents C(=N-W-D) or S; B represents S or C(-NH-W-D); when: A represents C(=N-W-D) and B represents S then the bond between B and the NH atom is a single bond; or A represents S and B represents C(-NH-W-D) then the bond between B and the NH atom is a double bond; X represents -Q-[CR x R y ] n -; W represents -[CR x R y ] m - or -C(O)-[CR x R y ] p -; Q represents a bond, -N(R a )-, -S-, or -O-; A 1 to A 5 respectively represent C(R 1 ), C(R 2 ), C(R 3 ), C(R 4 ) and C(R 5 ), or, alternatively, up to two of A 1 to A 5 may independently represent N; D represents phenyl, pyridyl or pyrimidinyl optionally substituted by one or more R 6 groups, which compounds are useful in the treatment of cancer. |