| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08805c563877d2ec6e01bc3872dd8e89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c7b21ab23ac7073b54fdd2552e4d191
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b61486528e910979189f51c9bae06297
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c10c4187c948207e7bf7d8eb242e2e36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81390d80019c0e8db1f21030ed91bd68 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 |
| filingDate |
2010-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9915b6e72b47e6749cc87b7be5d6eb9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c112c3c0e1c66399d2c42a817e555829
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce18573bfd000f48395e66b16c23eeef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f549c08016da8f5c2002c486063a1d3c |
| publicationDate |
2010-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010146404-A1 |
| titleOfInvention |
Adamantane derivatives of aza-crown ethers and their use in treatment of tumor |
| abstract |
The invention relates to adamantane diaza-crown ether derivatives and the use of mono and diaza-crown ether adamantine derivatives in treatment, especially in tumor treatment. Adamantane aza-crown ethers were obtained by reaction of the corresponding adamantane derived tosylates or adamantane acid chlorides with mono- and diaza-18-crown-6. The prepared compounds showed moderate (monoaza-18- crown-6) to strong (diaza-18-crown-6) antiproliferative and cytotoxic activity on several tumor cell lines, revealing their potential for inhibiting the growth of other tumor cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114656422-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114656422-B |
| priorityDate |
2009-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |