| abstract |
A method for inhibiting the growth of drug resistant cells in a subject, comprising identifying a subject having drug resistant cells; and administering to the subject a compound or a pharmaceutically acceptable salt or ester thereof, that is a MDR1 -inverse agent. Also disclosed is a method of inhibiting cancer in a subject, comprising administering to the subject an antiproliferative agent, wherein the antiproliferative effect of the agent is potentiated by P-glycoprotein and the agent is a compound, or a pharmaceutically acceptable salt or ester thereof, that is a MDR1 -inverse agent. |