| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e750dad8139cd56a56a7d9dbf990722
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4021f8d8a53258a5a3615b4139dd1eee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9756e99f73d6675241b59b0afc45eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de20a2318ba2a9528ff12e8189935502 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
| filingDate |
2010-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05bad20bb758ecda731661306b2f81e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d216788c4a355c76ea1758cae1e359c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d109c340bb94e194b9a371795605ea0b |
| publicationDate |
2010-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010136981-A2 |
| titleOfInvention |
Meganuclease variants cleaving the genome of a pathogenic non-integrating virus and uses thereof |
| abstract |
An I-C re I variant, wherein at least one of the two l-C re l monomers has at least two substitutions, one in each of the two functional subdomains of the LAGLIDADG core domain situated from positions 26 to 40 and 44 to 77 of I-C re I, said variant being able to cleave a DNA target sequence from the genome of a non- integrating virus, inparticular herpes simplex virus (HSV) or Hepatitis B virus (HBV) for use in genome engineering and for in vivo and ex vivo (gene cell therapy) genome therapy as well as the treatment of a virus infection. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022241215-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012010976-A3 |
| priorityDate |
2009-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |