http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010135411-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_509071f8c0967630e9f25be20d7f196a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b6121dedd894b3f760906b68697d616 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f882f281f6bd2513804e42fb6d7f121e |
| publicationDate | 2010-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2010135411-A2 |
| titleOfInvention | Aurora-a copy number and sensitivity to inhibitors |
| abstract | Disclosed is the identification, provision and use of biomarkers predictive of sensitivity or resistance to AAI inhibitors and products and processes related thereto. Specifically, a method is described for selecting a cancer patient predicted to benefit from therapeutic administration of an AAI inhibitor, an agonist thereof, or a drug having substantially similar biological activity as AAI inhibitor. Also described is a method to identify molecules that interact with the AAI pathway to allow or enhance responsiveness to AAI inhibitors, as well as a plurality of polynucleotides or antibodies for the detection of the copy number or expression of genes that are indicative of sensitivity or resistance to AAI inhibitors, an agonist thereof, or a drug having substantially similar biological activity as AAI inhibitors. A method to identify a compound with the potential to enhance the efficacy of AAI inhibitors is also described. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9568483-B2 |
| priorityDate | 2009-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.