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publicationDate 2010-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010130782-A1
titleOfInvention Use of the gtpase rab27b to diagnose and treat poor prognosis estrogen-receptor-positive breast cancer
abstract The present invention relates to evaluating the prognosis of patients with estrogen receptor- positive breast cancer on the basis of Rab27B expression. The invention further relates to a kit comprising an assay for measuring Rab27B levels in said patients and to the usage of Rab27B as a target to screen for drugs capable of inhibiting or diminishing metastasis of said cancer. Furthermore, the invention discloses compounds which can be used to treat estrogen receptor- positive breast cancer.
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