| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f94afa52c99b30d3112696816048a8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c073f4f62919331e693a628ccb7eda20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a96b8962f4882dc2a1f14125339db8b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd7ec16a659b720d93f60765ab54e1ef |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-203 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2010-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f6ccdb7f56b5ac1f818f2afe3f39af1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d49f1e5097de42f789e96b792176b39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca49f7571cff172b18ec11716ed81976 |
| publicationDate |
2010-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010128128-A1 |
| titleOfInvention |
Dhx36 / rhau knockout mice as experimental models of muscular dystrophy |
| abstract |
The present invention provides a genetically-modified non-human animal whose somatic and germ cells contain a gene encoding an altered form of an DHX36 gene, the altered DHX36 gene having been targeted to replace a wild-type DHX36 gene into the animal or an ancestor of the animal at an embryonic stage using embryonic stem cells. An ideal use of the genetically-modified non-human animal of the invention is the use as an experimental model for muscular dystrophy, e.g. spinal muscular atrophy, to identify e.g. new treatments for muscular dystrophy and or study its pathogenesis. |
| priorityDate |
2009-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |