Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cda08695212c84100769f1bd2261686f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdaa051e13e3c86096899b9593c7d095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b4307f910705eb86230f4b05183ca49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38d1af24d1605b4d2e03894ae5314dfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b9bb791944405c37c57b4906bf05cec http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca73af1522d146cc5d2c94f1291043ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_874d26b9f6c2dfda8b80d5944468bce5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2010-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_731d5e410d2d52bf26998b178664ae49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c82bd4c0e00506f0fab6485b97089ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c9e202cb532f1a06ff94e2f6b094e2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d27da23b2455b9c815dfc0dfa6764b0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6cde623d2d43baaa913d5436fddd134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1745e05f86dda13483dbeb061e76ba02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cb6da94e5f63eea9ef91ed37522596d |
publicationDate |
2010-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010121123-A1 |
titleOfInvention |
Methods and gene expression signature for assessing ras pathway activity |
abstract |
Methods, biomarkers, and expression signatures are disclosed for assessing the regulation status of RAS pathway signaling in a cell sample or subject. More specifically, several aspects of the invention provide a set of genes which can be used as biomarkers and gene signatures for evaluating RAS pathway deregulation status in a sample; classifying a cell sample as having a deregulated or regulated RAS signaling pathway; determining whether an agent modulates the RAS signaling pathway in sample; predicting response of a subject to an agent that modulates the RAS signaling pathway; assigning treatment to a subject; and evaluating the pharmacodynamic effects of cancer therapies designed to regulate RAS pathway signaling. |
priorityDate |
2009-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |