http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010118300-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b675d96dfbae58a03ea7e930f8cd2026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3be337f45b15b08f80b075ede93f2f7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2010-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c967805c46f13c5413a81631975a2cf1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f51dbf2c94d3930bb5a07b6831a20d49 |
| publicationDate | 2010-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2010118300-A1 |
| titleOfInvention | Conformational epitope initiated signal amplification |
| abstract | This invention relates to a method to generate a signal used to detect the presence or quantity of a biomarker in a sample. The signal generating reaction is initiated when the biomarker under assay interacts with a specific binding partner. The interaction produces a structural change in the binding partner that is recognized by additional binding partners capable of generating a signal. The reaction produces a localized cluster of signaling molecules that can be detected above background. The signaling cluster is detectable within minutes when interrogated in a chamber of specific dimensions. The presence of the signaling clusters is a qualitative indication of the presence of the analyte, while the number of signaling clusters detected is a direct quantification of the number of biomarker molecules in the sample. The reaction can be formatted to detect proteins, nucleic acids, cells or other informative biomarkers. |
| priorityDate | 2009-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.