| abstract |
The present invention relates to substituted tetrahydropyrazolo-pyrido-azepine compounds of formula (I) and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof, or a pharmaceutically acceptable salt or ester thereof, wherein: X 1 , X 2 ; and X 3 , together with the two carbon atoms numbered "1" and "2", form a ring selected from (a), (b) and (c). |