Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a903c8bf331dc01e5cd000fa6a6de3da http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78829060a03f98e07b58fa011c438ded http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38af75f55c146d8cfae73a0aa660fa33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_241c3d4e236532a2e822eb39f56b1be9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14f8866fd10a12d3cc3afb0e2240920d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb277c9a19c49a8070bd29c602c97a15 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
filingDate |
2010-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bcae3836b9ce8a1906cfe44e7991047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f90455c474bdca666c5cf93c7145da9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c51e7d1e787fb4f25917d908c09c2bb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_056cbc7414abd27c74293941ce8ed16f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a8c42fdd2309df894cd2b05f9abb4c |
publicationDate |
2010-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010113753-A1 |
titleOfInvention |
Prophylactic or therapeutic agent for retinal diseases and method for preventing or treating retinal diseases, each comprising jnk (c-jun n-terminal kinase)-inhibiting peptide, and use of the peptide |
abstract |
The intravitreal administration of a JNK-inhibiting peptide which comprises (a) at least either one of the JNK-inhibiting sequences depicted in SEQ ID NO:1 and SEQ ID NO:2 and (b) at least either one of the transfer sequences depicted in SEQ ID NO:3 and SEQ ID NO:4 and has a length shorter than 150 amino acid residues wherein at least one amino acid residue is a D-amino acid residue can prevent the occurrence of spermidine-induced damage of retinal pigment epitheliums, tunicamycin-induced visual cell injury, and laser-induced choroidal neovascularization. Therefore, the JNK-inhibiting peptide is useful for the prevention or treatment of retinal diseases. By using the JNK-inhibiting peptide, it becomes possible to provide a medicinal agent and a method both of which can prevent or treat retinal diseases through topical administration in eyes. It also becomes possible to provide use of the JNK-inhibiting peptide for the production of the medicinal agent. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9624267-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779628-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013091670-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10596223-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10967038-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9610330-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013091896-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012048721-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012048893-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016089413-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624948-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013540770-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11331364-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015197097-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014206426-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2902035-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3718555-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019060392-A1 |
priorityDate |
2009-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |