| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7d9efad87e0fb61ac65777be53aa204
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdc7a8408d48b5c3c409292a0544138a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4bae3b8115a67ed0e728a0e1492c631
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_341be1c29b315dd9f03d3405f7deed42 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-711 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
| filingDate |
2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_526f0373b9829d83ed40763db1e90b54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a870e8e1e75721cb28673405217d7ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55a02abf8cabccef44dce0112f5309b8 |
| publicationDate |
2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010109544-A1 |
| titleOfInvention |
Composition for external application containing nucleic acid as active ingredient |
| abstract |
Disclosed is a composition for external application, which contains a nucleic acid and has good skin permeability. A nucleic acid is dissolved in an ionic liquid of a triethanol amine salt or a diethanol amine salt of a lower fatty acid. The resulting solution is mixed with an organic solvent and/or an ionic liquid of a triisopropanol amine salt or a diisopropanol amine salt of a fatty acid to adjust the solubility of the nucleic acid, thereby preparing a mixed ionic liquid solution containing the nucleic acid. The ionic liquid solution is mixed with and dispersed in a base material for an ointment or a matrix adhesive patch, thereby producing a non-aqueous composition for external application. The composition for external application containing a nucleic acid has excellent skin permeability. By varying the types of the nucleic acid employed, it becomes possible to provide compositions for external application suitable for various purposes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019526626-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7179354-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8705946-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014131975-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786597-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109789216-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109789216-A |
| priorityDate |
2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |