http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010104341-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a251ae79dd7a008d95010b238c6aa1f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_027e51e61207e095fde80f5505f427f3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56961 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2010-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50e0131b4251fecfe03604ebc37bc53e |
publicationDate | 2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2010104341-A2 |
titleOfInvention | Compositions for diagnosis of fungal infections |
abstract | The present invention relates to a marker for diagnosis of fungal infections, which is sequentially activated in vivo in the presence of ß-1,3-glucan, which activates the Toll signaling pathway, to compositions for diagnosis of fungal infections in a specimen, and to a method for producing antibacterial substances. More particularly, the present invention has proved that a GNBP3-mediated ß-1,3-glucan recognition signal reaches pro-Spaetzle using three serine proteases as mediators, namely, modular serine protease (MSP), Spaetzle-processing enzyme activating enzyme (SAE), and Spaetzle-processing enzyme (SPE). Proteins involved with ß-1,3-glucan recognition signaling can be effectively used as compositions for detecting fungal infections in blood samples or the like. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110295158-A |
priorityDate | 2009-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.