| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09f438c39808c6250edbf9863c71a514
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71fa25ac77a105824c3a7e9386f66594
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bfb1eb4d545aed9bcc8be1f70daf000
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbaf0ef5c7339bb0fa569c4abaf9a53f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_751ac5caa461332bad722817a13a1317
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a30c05b8bcded87fe188b7fb6a5094e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4827ad54412494d6d529f762871c94c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-68 |
| filingDate |
2010-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5829bc5059ae809a5e477e37bce04ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c854b86162108c922423cb1ce4abe071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0d3b226db4865bc79ac460afd5e1e79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e7873a697c67f174fe5dc871b84cc3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ea2a4db3e1a22d7b10612abc53950c3 |
| publicationDate |
2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010104307-A2 |
| titleOfInvention |
Pharmaceutical compositions for treating or preventing diseases caused by the translocation of gsk3 from the cell nucleus to the cytoplasm, containing compounds for inhibiting the translocation of gsk3 from the cell nucleus to the cytoplasm |
| abstract |
The present invention relates to pharmaceutical compositions for treating or preventing diseases caused by the translocation of GSK3 from the cell nucleus to the cytoplasm, containing compounds for inhibiting the translocation of GSK3 from the cell nucleus to the cytoplasm. More particularly, the present invention relates to pharmaceutical compositions for inhibiting the growth or the metastatis of cancer cells and pharmaceutical compositions for treating autoimmune diseases, containing novel compounds for inhibiting the translocation of GSK3 from the cell nucleus to the cytoplasm. The present invention provides compositions for inhibiting the outbreak and progression of diseases caused by a decrease in the concentration of GSK3 in the nucleus and the translocation of GSK from the cell nucleus to the cytoplasm. The compounds according to the present invention inhibit the nuclear export function of GSK3 performed by Axin, and increase the concentration of GSK3 in the nucleus, and can thus be valuably used in treating or preventing a variety of diseases caused by a decrease in the concentration of GSK3 in the nucleus. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10208032-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020073512-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10206877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016512194-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019108391-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019131569-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110105340-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110105340-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017502960-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9732080-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10538520-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766899-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10434112-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10081621-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10071979-B2 |
| priorityDate |
2009-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |